This article aims to determine an association of a genomic subtyping classifier (GSC) with pathological upstaging in multi-institutional cohort of patients with cT1-T2 UC treated with RC.
This course compiles the most recent clinical guidelines edited by the EAU in relation to Primary Urethral Carcinoma. Each Learning Unit consists of multiple choice questions that you can answer by navigating to the corresponding chapter of the Primary Urethral Carcinoma guideline.
The results suggest that FGFR3 mutations (driver effect) have a distinct functional role than FGFR3 over-expression (passenger effect). Hence, patients with FGFR3 mutations may be more likely to benefit from anti-FGFR3 therapy than patients with only over-expression of FGFR3.