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FGFR3 mutations and their relation to FGFR3 expression and clinical outcome in a large radical cystectomy cohort: Implications for anti-FGFR3 bladder cancer treatment?

  • Mertens L.S. 1,
  • Van Rhijn B.W.G. 1,
  • Mayr R. 2,
  • Bostrom P.J. 3,
  • Marquez M. 4,
  • Zwarthoff E.C. 5,
  • Boormans J.L. 6,
  • Abas C. 5,
  • Van Leenders G. 5,
  • Neuzillet Y. 1,
  • Van Der Heijden M.S. 7,
  • Real F.X. 4,
  • Stohr R. 8,
  • Zlotta A.R. 9,
  • Eckstein M. 8,
  • Soorojebally Y. 10,
  • Burger M. 2,
  • Radvanyi F. 10,
  • Sirab N. 10,
  • Pouessel D. 10,
  • Van Der Kwast T.H. 11,
  • Malats N. 4,
  • Hartmann A. 8,
  • Allory Y. 10,
  • Zuiverloon T. 6
1 Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Dept of Surgical Oncology, Urology, Amsterdam, The Netherlands 2 Caritas St Joseph Medical Center, University of Regensburg , Dept. of Urology, Regensburg, Germany 3 University of Turku, Dept. of Urology, Turku, Finland 4 CNIO, Dept. of Genetic Molecular Epidemiology and Cancer Biology, Madrid, Spain 5 Erasmus MC, Dept. of Pathology, Rotterdam, The Netherlands 6 Erasmus MC, Dept. of Urology, Rotterdam, The Netherlands 7 Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Dept. of Medical Oncology, Amsterdam, The Netherlands 8 University of Erlangen, Dept. of Pathology, Erlangen, Germany 9 University Health Network, Dept. of Urology, Toronto, Canada 10 Institut Curie, Dept. of Pathology, Paris, France 11 University Health Network, Dept. of Pathology, Toronto, Canada

Publication: March 2019