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Incidence, Characteristics and Implications of Thromboembolic Events in Patients with Muscle Invasive Urothelial Carcinoma of the Bladder Undergoing Neoadjuvant Chemotherapy

  • Duivenvoorden WC,
  • Daneshmand S,
  • Canter D,
  • Lotan Y,
  • Black PC,
  • Abdi H,
  • van Rhijn BW,
  • Fransen van de Putte EE,
  • Zareba P,
  • Koskinen I,
  • Kassouf W,
  • Traboulsi SL,
  • Kukreja JE,
  • Boström PJ,
  • Shayegan B,
  • Pinthus JH

Publication: J Urol., Volume 196, Issue 6, December 2016, Pages 1627-1633

https://www.ncbi.nlm.nih.gov/pubmed/27312316

Piotr Chlosta

The overall incidence of thromboembolic events (TEEs) in patients undergoing neoadjuvant chemotherapy before radical cystectomy was 14%, with 58% of events occurring preoperatively. Prophylaxis to prevent TEEs may need to be initiated earlier in these patients, during the NAC treatment course.